Microdosing GLP-1/GIP Peptides These molecules didn't start as weight-loss drugs, and at sub-therapeutic doses their strongest signal may not be the scale at all — it's inflammation, endothelial function, and organ protection. Semaglutide and tirzepatide are usually framed as appetite drugs. But GIP and GLP-1 receptors sit on the heart, kidney, liver, cartilage, mast cells, and T-cells — tissue that has nothing to do with hunger. Microdosing asks a different question than the pharmaceutical industry's high-dose, weight-loss-first framing: can we access those receptor effects — lower inflammation, better insulin signaling, improved endothelial function — at doses well below what's needed to move the scale? The honest answer is: probably, in several organ systems, but the formal microdose-specific trials are only just getting underway. A Brief History — How We Got Here GLP-1/GIP are found naturally in our body. The were discovered after observatio...
A SIMPLE KETOGENIC DIET A Beginner's Complete Guide to Keto Eating & Blood Level Monitoring You don't need a PhD in nutrition to succeed on keto. This guide strips everything back to the fundamentals — what to eat, what to avoid, and how to know with confidence that your body has made the metabolic switch. Thousands of people have transformed their health with this approach, and you can too. Let's keep it simple and get you started. 1. What Is the Ketogenic Diet? The ketogenic (keto) diet is a very low-carbohydrate, high-fat eating plan that shifts your body's primary fuel source from glucose (sugar) to ketones — molecules your liver produces from fat. This metabolic state is called ketosis, and it's where the magic happens. When you drastically reduce carbohydrates to under 20–50 grams per day, your body depletes its glucose reserves within 2–3 days and begins burning stored fat for energy. The result: steady energy, reduced hunger, and ...